Sir Alex Ferguson has told youngsters Darron Gibson and Danny Welbeck they will start Sunday's Carling Cup final.
Rafael Da Silva is out with a fractured ankle but Wayne Rooney should start as he continues to build match fitness.
Tottenham's Robbie Keane, Wilson Palacios, Carlo Cudicini and Pascal Chimbonda are all cup-tied.
Jamie O'Hara (hip) has declared himself fit but on-loan Fraizer Campbell cannot play against his parent club and Ledley King (knee) will have a fitness test.
Ferguson said next Wednesday's Premier League trip to Newcastle is a bigger priority for his side than the Carling Cup final.
"We obviously want to win because the winning mentality in the club is why we have been successful, but we know what our priorities are and that will affect the team that I pick on Sunday," he said.
Ferguson promises to continue youth policy
"We have a big game at Newcastle on Wednesday and the priority for us will always be the Premier League and the Champions League.
"The Premier League is the only place to be and Harry Redknapp is well aware of that judging by the team he picked in the Uefa Cup on Thursday."
But Ferguson dismissed suggestions United were taking the game lightly by travelling down to London just 24 hours before the game and insisted that, unlike some other countries, all cup competitions are taken seriously in Britain.
"We have always travelled down to the League Cup final the day before the game," he said.
"Some countries don't bother about the cup competitions but the British mentality is for their team to win, it doesn't matter what competition it is.
"That competitive streak goes through supporters, players and directors. There is an apocryphal story about a manager getting sacked after three successive defeats on the Pools Panel. That sums up our country."
606: DEBATE
How can we lose the Cup Final on Sunday?Paddy_The_Red_DevilTottenham manager Harry Redknapp said United were his dream opponents in Sunday's final.
"You have to look forward to playing Manchester United," Redknapp said.
"When people asked when Derby won the first leg of their semi-final if it would be great if they could pull it off, I said no way.
"No disrespect but I really wanted to play United in the final. It's a way for you to test yourself against the best.
"They are the best team in Europe, and they were tremendous against Inter Milan in the Champions League on Tuesday.
"We've had some good games against the big teams this season. At home with United we drew, with a good performance, so we've got players who can play against anyone.
"Hopefully, playing on a big stage on Sunday will bring best out of them and we'll get the bit of luck that you always need against the best teams."
Redknapp confident of Cup upset
Redknapp felt his side, who sit five points above the Premier League drop zone, could have been staring at relegation if they had not been boosted by their run to Wembley.
Spurs took a 4-1 lead into their semi-final second leg against Burnley but were 3-0 with two minutes to go at Turf Moor, before two late goals saw them scrape through.
"It would certainly have made it very, very difficult for us to have lifted ourselves - the shame of it all, of being 4-1 up and going out the competition," said Redknapp.
"That was as angry as I have been since I have been here. I was very, very low. Imagine how low we would have been if we had gone out.
"If we had gone out we would have been in desperate trouble because I don't know how we would have recovered from that."
Tottenham (from): Gomes, Alnwick, Corluka, Assou-Ekotto, Woodgate, King, Bentley, Jenas, Modric, Zokora, Lennon, Pavyluchenko, Bent, O'Hara, Huddlestone, Bale, Dawson, Gunter, Giovani, Taarabt.
Man Utd (from): Foster, Kuszczak, Neville, Fabio, Gibson, Evans, Vidic, Ferdinand, O'Shea, Evra, Welbeck, Anderson, Carrick, Fletcher, Park, Scholes, Nani, Ronaldo, Giggs, Tevez, Rooney.